SLC33A1

Across TCGA pan-cancer cohorts, SLC33A1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC33A1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC33A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC33A1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where SLC33A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.607	1.000	.003	25	view →
LUAD	DFS	Tertile	All	0.981	0.843	.004	15	view →
HNSC	DFS	Tertile	III,IV	0.905	1.000	.019	4	view →
GBM	OS	Quartile	All	0.571	0.920	.013	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC33A1–CCRCC (OS)

Open the CCRCC breakdown →