SLC33A1

Across TCGA cell cohorts, SLC33A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,009 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC33A1-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, Post-translational protein targeting to membrane, translocation, and ERAD pathway. Each is linked with SLC33A1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLC33A1-to-partner and partner-to-SLC33A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by SLC33A1-low versus SLC33A1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC33A1→partner) and Y-score (partner→SLC33A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to endoplasmic reticulum stress →	+0.093	+0.906	.005	.005	3	19
OESOPHAGUS	Post-translational protein targeting to membrane, translocation →	+0.133	+0.740	<.001	<.001	3	17
PANCREAS	ERAD pathway →	+0.103	+0.883	<.001	.001	3	16
BONE	Cotranslational protein targeting to membrane →	+0.147	+0.702	<.001	<.001	3	16
PANCREAS	Regulation of response to endoplasmic reticulum stress →	+0.063	+0.681	.008	.001	3	15
PANCREAS	Endoplasmic reticulum unfolded protein response →	+0.119	+0.899	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,009 associations by consensus.

Response to endoplasmic reticulum stress by SLC33A1 expression — OESOPHAGUS

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