SLC33A1

Across TCGA cell cohorts, SLC33A1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC33A1-associated genes across cancer lineages are PRG3, C1QA, and PRAMEF10. Each is linked with SLC33A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC33A1-to-partner and partner-to-SLC33A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRG3 grouped by SLC33A1-low versus SLC33A1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC33A1→partner) and Y-score (partner→SLC33A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRG3 →	+0.020	+4.058	<.001	.007	3	1
LUNG_SCLC	C1QA →	+0.290	+4.070	<.001	.003	3	1
LUNG_SCLC	PRAMEF10 →	+0.708	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF17 →	+0.008	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF33 →	+0.392	+4.614	<.001	<.001	3	1
LUNG_SCLC	OR13C5 →	+0.038	+5.232	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PRG3 by SLC33A1 expression — LUNG_SCLC

Explore this box plot interactively →