SLC31A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC31A2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC31A2-associated genes across cancer lineages are MIR6133, RNU6-644P, and NDUFS5P4. Each is linked with SLC31A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC31A2-to-partner and partner-to-SLC31A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6133 grouped by SLC31A2-low versus SLC31A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC31A2→partner) and Y-score (partner→SLC31A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6133 →+0.759+4.982<.001.00931
UCECRNU6-644P →+0.595+4.982.007.00931
UCECNDUFS5P4 →+0.288+5.420.002.00531
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MIR6133 by SLC31A2 expression — UCEC

Box plot of MIR6133 in SLC31A2-low vs SLC31A2-high samples in UCEC.

Explore this box plot interactively →

Exploration