SLC31A1

Across TCGA patient cohorts, SLC31A1 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC31A1-associated genes across cancer lineages are Tuberin_pT1462, Rab25, and STAT5a. Each is linked with SLC31A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC31A1-to-partner and partner-to-SLC31A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by SLC31A1-low versus SLC31A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC31A1→partner) and Y-score (partner→SLC31A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin_pT1462 →	+0.376	+3.179	.001	.010	3	1
UCEC	Rab25 →	-0.366	-3.321	.035	.010	2	1
UCEC	STAT5a →	+0.426	+3.321	.042	.010	2	1
UCEC	ASNS →	+0.715	+3.169	<.001	.019	2	1
UCEC	Di-Ras3 →	-0.175	-3.321	.024	.010	2	1
UCEC	14-3-3_beta →	-0.164	-3.308	.001	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Tuberin_pT1462 by SLC31A1 expression — UCEC

Explore this box plot interactively →