SLC31A1

Across TCGA cell cohorts, SLC31A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,424 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC31A1-associated GO terms across cancer lineages are Vascular endothelial growth factor receptor-2 signaling pathway, Vesicle cargo loading, and Proteasome regulatory particle assembly. Each is linked with SLC31A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC31A1-to-partner and partner-to-SLC31A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vascular endothelial growth factor receptor-2 signaling pathway grouped by SLC31A1-low versus SLC31A1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC31A1→partner) and Y-score (partner→SLC31A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Vascular endothelial growth factor receptor-2 signaling pathway →	+0.273	+1.118	<.001	.009	3	18
BONE	Vesicle cargo loading →	+0.128	+0.867	<.001	.001	3	10
LUNG_NSCLC_LUAD	Proteasome regulatory particle assembly →	+0.104	+0.556	<.001	<.001	3	10
CNS	Nucleotide-sugar transmembrane transport →	+0.094	+0.623	<.001	<.001	3	9
CNS	Endoplasmic reticulum to cytosol transport →	+0.109	+0.602	<.001	.002	3	9
CNS	Retrograde protein transport, ER to cytosol →	+0.109	+0.602	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,424 associations by consensus.

Vascular endothelial growth factor receptor-2 signaling pathway by SLC31A1 expression — BLOOD_Myeloma

Explore this box plot interactively →