SLC30A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC30A9 mutation is significantly associated with the RNA expression of many other genes, with 1,117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A9-associated genes across cancer lineages are MIR4716, SAPCD2P2, and HMGB1P7. Each is linked with SLC30A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A9-to-partner and partner-to-SLC30A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4716 grouped by SLC30A9-low versus SLC30A9-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A9→partner) and Y-score (partner→SLC30A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR4716 →+0.309+4.268<.001.00832
SKCMSAPCD2P2 →+0.024+3.422<.001.00632
COADHMGB1P7 →+0.567+3.154<.001.00632
LUADOR7E162P →+0.116+4.568<.001.00432
READRPL7P31 →+0.171+4.626<.001.00432
READRNU6-893P →+0.733+4.445<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,117 associations by consensus.

MIR4716 by SLC30A9 expression — BRCA

Box plot of MIR4716 in SLC30A9-low vs SLC30A9-high samples in BRCA.

Explore this box plot interactively →

Exploration