SLC30A9

Across TCGA patient cohorts, SLC30A9 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A9-associated genes across cancer lineages are 14-3-3_beta, Shc_pY317, and beta-Catenin. Each is linked with SLC30A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC30A9-to-partner and partner-to-SLC30A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by SLC30A9-low versus SLC30A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A9→partner) and Y-score (partner→SLC30A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.084	-2.432	.017	.018	3	3
UCEC	Shc_pY317 →	-0.139	-1.415	.009	.043	3	2
UCEC	beta-Catenin →	+0.418	+1.874	.019	.049	3	2
UCEC	Caspase-8 →	-0.240	-2.880	.006	.001	3	2
UCEC	Fibronectin →	-0.262	-2.212	.024	.010	3	1
UCEC	ACC1 →	+0.267	+3.183	.038	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

14-3-3_beta by SLC30A9 expression — UCEC

Explore this box plot interactively →