SLC30A8

Across TCGA patient cohorts, SLC30A8 mutation is significantly associated with the RNA expression of many other genes, with 2,861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A8-associated genes across cancer lineages are MIR5689, ARF1P1, and ESS2. Each is linked with SLC30A8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC30A8-to-partner and partner-to-SLC30A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5689 grouped by SLC30A8-low versus SLC30A8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A8→partner) and Y-score (partner→SLC30A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR5689 →	+0.098	+2.145	<.001	.005	3	3
LIHC	ARF1P1 →	+0.060	+4.758	<.001	.006	3	2
UCEC	ESS2 →	+0.231	+2.137	.001	<.001	3	2
UCEC	CINP →	+0.281	+1.731	<.001	<.001	3	2
SKCM	ACTR5 →	+0.271	+2.000	.002	.002	3	2
UCEC	SGTA →	+0.489	+2.606	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,861 associations by consensus.

MIR5689 by SLC30A8 expression — SKCM

Explore this box plot interactively →