SLC30A8

Across TCGA patient cohorts, SLC30A8 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A8-associated genes across cancer lineages are eIF4E, FoxM1, and INPP4B. Each is linked with SLC30A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A8-to-partner and partner-to-SLC30A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC30A8-low versus SLC30A8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A8→partner) and Y-score (partner→SLC30A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.148	+1.432	.017	.005	3	2
UCEC	FoxM1 →	+0.150	+1.241	.048	.015	3	2
UCEC	INPP4B →	-0.231	-1.419	.015	.005	3	2
UCEC	Notch1 →	+0.156	+1.637	<.001	.001	3	2
UCEC	p27_pT198 →	+0.079	+1.584	.011	.034	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.389	-1.584	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

eIF4E by SLC30A8 expression — UCEC

Explore this box plot interactively →