SLC30A8

Across TCGA cell cohorts, SLC30A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,362 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC30A8-associated GO terms across cancer lineages are Host-mediated activation of viral genome replication, Transcription elongation-coupled chromatin remodeling, and Plasma membrane repair. Each is linked with SLC30A8 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC30A8-to-partner and partner-to-SLC30A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Host-mediated activation of viral genome replication grouped by SLC30A8-low versus SLC30A8-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A8→partner) and Y-score (partner→SLC30A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Host-mediated activation of viral genome replication →	+0.069	+0.391	<.001	.003	3	4
SKIN	Transcription elongation-coupled chromatin remodeling →	+0.044	+0.488	.006	.006	3	3
LUNG_NSCLC_LUSC	Plasma membrane repair →	+0.133	+0.039	<.001	.002	3	3
BLOOD_Lymphoma	Negative regulation of purine nucleotide metabolic process →	+0.089	+0.473	<.001	.006	3	3
BLOOD_Lymphoma	Negative regulation of nucleotide metabolic process →	+0.089	+0.473	<.001	.006	3	3
BLOOD_Lymphoma	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.129	+0.269	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,362 associations by consensus.

Host-mediated activation of viral genome replication by SLC30A8 expression — BLOOD_Lymphoma

Explore this box plot interactively →