SLC30A5

Across TCGA pan-cancer cohorts, SLC30A5 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SLC30A5 data layer compared with 26 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC30A5 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC30A5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where SLC30A5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.873	0.560	.001	22	view →
CCRCC	OS	Median	All	0.558	1.000	<.001	15	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	13	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	8	view →
OV	DFS	Median	All	0.942	0.690	.023	4	view →
UCEC	OS	Quartile	All	1.000	0.906	.041	2	view →
LSCC	DFS	Tertile	II,III,IV	0.891	1.000	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SLC30A5–HNSC (OS)

Open the HNSC breakdown →