SLC30A5

Across TCGA patient cohorts, SLC30A5 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A5-associated genes across cancer lineages are AMPK_alpha, eEF2, and EGFR_pY1068. Each is linked with SLC30A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A5-to-partner and partner-to-SLC30A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMPK_alpha grouped by SLC30A5-low versus SLC30A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A5→partner) and Y-score (partner→SLC30A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AMPK_alpha →	-0.163	-2.115	.033	.017	3	2
UCEC	eEF2 →	+0.282	+1.906	.049	.016	3	1
UCEC	EGFR_pY1068 →	-0.266	-2.415	.008	.003	3	1
UCEC	ERK2 →	+0.265	+3.459	<.001	.005	3	1
UCEC	FoxM1 →	+0.262	+2.415	.011	.003	3	1
UCEC	Gab2 →	+0.347	+1.906	.015	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

AMPK_alpha by SLC30A5 expression — UCEC

Explore this box plot interactively →