SLC30A5

Across TCGA cell cohorts, SLC30A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,000 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC30A5-associated GO terms across cancer lineages are Insulin processing, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Positive regulation of translational initiation. Each is linked with SLC30A5 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC30A5-to-partner and partner-to-SLC30A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Insulin processing grouped by SLC30A5-low versus SLC30A5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A5→partner) and Y-score (partner→SLC30A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Insulin processing →	+0.206	+0.643	<.001	<.001	3	14
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.127	+0.815	.001	.001	3	11
BLOOD_Lymphoma	Positive regulation of translational initiation →	+0.089	+0.679	.003	<.001	2	12
LUNG_NSCLC_LUAD	Golgi vesicle transport →	+0.046	+0.526	<.001	.001	3	9
LIVER	Regulation of protein exit from endoplasmic reticulum →	+0.139	+0.753	.005	<.001	3	9
STOMACH	Positive regulation of protein exit from endoplasmic reticulum →	+0.111	+0.798	.004	.007	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,000 associations by consensus.

Insulin processing by SLC30A5 expression — LUNG_SCLC

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