SLC30A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC30A5 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC30A5-associated genes across cancer lineages are ELOA3DP, OR13G1, and ASB17. Each is linked with SLC30A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A5-to-partner and partner-to-SLC30A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by SLC30A5-low versus SLC30A5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A5→partner) and Y-score (partner→SLC30A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEELOA3DP →+0.036+4.273<.001.00632
LARGE_INTESTINEOR13G1 →+0.024+4.415<.001.00731
OVARYASB17 →+0.023+5.807<.001.00131
UPPER_AERODIGESTIVE_TRACTOR9A4 →+0.077+4.050.004.00231
UPPER_AERODIGESTIVE_TRACTSLC13A1 →+0.027+3.510<.001.00731
STOMACHZNF835 →+0.151+4.442<.001.00211
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ELOA3DP by SLC30A5 expression — LARGE_INTESTINE

Box plot of ELOA3DP in SLC30A5-low vs SLC30A5-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration