SLC30A2

Across TCGA patient cohorts, SLC30A2 mutation is significantly associated with the RNA expression of many other genes, with 989 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A2-associated genes across cancer lineages are IL21, MIR6859-2, and TUBGCP5. Each is linked with SLC30A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A2-to-partner and partner-to-SLC30A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL21 grouped by SLC30A2-low versus SLC30A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A2→partner) and Y-score (partner→SLC30A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IL21 →	+0.144	+2.541	<.001	<.001	3	2
UCEC	MIR6859-2 →	+0.333	+2.231	<.001	.004	3	1
UCEC	TUBGCP5 →	+0.462	+4.032	.003	<.001	3	1
UCEC	TRBV18 →	+0.760	+3.332	<.001	.005	3	1
UCEC	TRAJ36 →	+0.631	+2.146	<.001	.006	3	1
UCEC	MIR8071-2 →	+0.897	+2.502	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 989 associations by consensus.

IL21 by SLC30A2 expression — UCEC

Explore this box plot interactively →