SLC30A2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC30A2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A2-associated genes across cancer lineages are Epithelial cells, Basophils, and Class-switched memory B-cells. Each is linked with SLC30A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A2-to-partner and partner-to-SLC30A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by SLC30A2-low versus SLC30A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A2→partner) and Y-score (partner→SLC30A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEpithelial cells →-0.084-1.991.005.03131
UCECBasophils →+0.173+2.222.016.01131
UCECClass-switched memory B-cells →-0.063-4.000.009<.00121
UCECiDC →-0.160-2.222.023.01121
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Epithelial cells by SLC30A2 expression — UCEC

Box plot of Epithelial cells in SLC30A2-low vs SLC30A2-high samples in UCEC.

Explore this box plot interactively →

Exploration