SLC30A2

Across TCGA cell cohorts, SLC30A2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC30A2-associated genes across cancer lineages are CD1C, MCHR2, and MS4A10. Each is linked with SLC30A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A2-to-partner and partner-to-SLC30A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD1C grouped by SLC30A2-low versus SLC30A2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A2→partner) and Y-score (partner→SLC30A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CD1C →	+0.022	+4.212	.004	.007	3	1
LARGE_INTESTINE	MCHR2 →	+0.021	+3.684	<.001	.006	3	1
BLOOD_Lymphoma	MS4A10 →	+0.006	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD1C by SLC30A2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →