SLC30A1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC30A1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC30A1 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SLC30A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC30A1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PDAC and HNSC are the cancer types where SLC30A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSQuartileAll0.8140.946.00138view →
HNSCDFSTertileAll0.8410.670.0153view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC30A1–PDAC (OS)

Kaplan–Meier survival curve for SLC30A1 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration