SLC30A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC30A1 mutation is significantly associated with the RNA expression of many other genes, with 193 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A1-associated genes across cancer lineages are RN7SL847P, RNU7-173P, and RPL7AP23. Each is linked with SLC30A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC30A1-to-partner and partner-to-SLC30A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL847P grouped by SLC30A1-low versus SLC30A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A1→partner) and Y-score (partner→SLC30A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL847P →+0.253+5.010<.001.00933
CESCRNU7-173P →+0.526+5.969<.001.00232
CESCRPL7AP23 →+0.067+5.103<.001.00832
CESCSLC29A4P1 →+0.061+5.969<.001.00232
SKCMMFN1P1 →+0.035+4.052.001.00532
SKCMIMP3P2 →+0.146+4.114.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

RN7SL847P by SLC30A1 expression — CESC

Box plot of RN7SL847P in SLC30A1-low vs SLC30A1-high samples in CESC.

Explore this box plot interactively →

Exploration