SLC30A1

Across TCGA patient cohorts, SLC30A1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A1-associated genes across cancer lineages are AR, Lck, and PR. Each is linked with SLC30A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A1-to-partner and partner-to-SLC30A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AR grouped by SLC30A1-low versus SLC30A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A1→partner) and Y-score (partner→SLC30A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AR →	-0.683	-3.000	.001	.037	1	2
UCEC	Lck →	+0.302	+3.000	.009	.037	1	1
UCEC	PR →	-0.329	-3.000	.023	.037	1	1
UCEC	Raptor →	-0.231	-3.000	.008	.037	1	1
UCEC	Annexin-1 →	+0.699	+3.000	.021	.037	1	1
UCEC	Caspase-7-cleavedD198 →	+1.492	+3.000	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

AR by SLC30A1 expression — UCEC

Explore this box plot interactively →