Across TCGA patient cohorts, SLC2A7 mutation is significantly associated with the RNA expression of many other genes, with 1,323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A7-associated genes across cancer lineages are SREBF2-AS1, BTBD6, and ITGB1BP1. Each is linked with SLC2A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC2A7-to-partner and partner-to-SLC2A7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A7→partner) and Y-score (partner→SLC2A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SREBF2-AS1 →	+0.379	+3.332	.003	.005	3	3
UCEC	BTBD6 →	+0.445	+2.436	<.001	.001	3	3
UCEC	ITGB1BP1 →	+0.403	+3.711	<.001	<.001	3	3
UCEC	PBK →	+0.765	+2.332	.003	<.001	3	3
UCEC	DERL2 →	+0.340	+2.864	.004	.001	3	3
UCEC	ACKR3 →	-1.013	-2.807	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,323 associations by consensus.

Exploration

SLC2A7 survival (RNA) · tumor vs normal (RNA) · all SLC2A7 data types