SLC2A6

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC2A6 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC2A6 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC2A6 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC2A6 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC and PDAC are the cancer types where SLC2A6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LSCCDFSMedianAll1.0000.360.00210view →
PDACOSTertileIII,IV0.5080.932.0333view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC2A6–LSCC (DFS)

Kaplan–Meier survival curve for SLC2A6 mass-spec protein-high vs -low samples in LSCC.

Open the LSCC breakdown →

Exploration