SLC2A6

Across TCGA patient cohorts, SLC2A6 mutation is significantly associated with the RNA expression of many other genes, with 4,563 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A6-associated genes across cancer lineages are TRIM37, CORO1C, and HACD3. Each is linked with SLC2A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC2A6-to-partner and partner-to-SLC2A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM37 grouped by SLC2A6-low versus SLC2A6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A6→partner) and Y-score (partner→SLC2A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRIM37 →	+0.502	+2.337	.002	.003	3	3
UCEC	CORO1C →	+0.642	+1.922	<.001	.003	3	3
UCEC	HACD3 →	+0.767	+2.169	<.001	<.001	3	3
UCEC	PRIM1 →	+0.851	+3.032	<.001	<.001	3	3
CESC	MBD3L3 →	+0.421	+5.144	<.001	.003	3	2
CESC	SSU72P8 →	+0.719	+5.144	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,563 associations by consensus.

TRIM37 by SLC2A6 expression — UCEC

Explore this box plot interactively →