SLC2A5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC2A5 mutation is significantly associated with the RNA expression of many other genes, with 1,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A5-associated genes across cancer lineages are RNU6-1127P, NCAPG, and YARS1. Each is linked with SLC2A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC2A5-to-partner and partner-to-SLC2A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1127P grouped by SLC2A5-low versus SLC2A5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A5→partner) and Y-score (partner→SLC2A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1127P →+0.283+4.136.001.00833
UCECNCAPG →+0.709+2.708.002.00333
UCECYARS1 →+0.401+2.141.007.00333
UCECTACC3 →+0.580+3.708.006<.00133
SKCMCOX5BP8 →+0.018+3.810<.001.00833
READRNU1-1 →+0.365+5.925<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,082 associations by consensus.

RNU6-1127P by SLC2A5 expression — COAD

Box plot of RNU6-1127P in SLC2A5-low vs SLC2A5-high samples in COAD.

Explore this box plot interactively →

Exploration