SLC2A5

Across TCGA cell cohorts, SLC2A5 mutation is significantly associated with the drug of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A5-associated genes across cancer lineages are 5-Fluorouracil, Eg5_9814, and 50869. Each is linked with SLC2A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A5-to-partner and partner-to-SLC2A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-Fluorouracil grouped by SLC2A5-low versus SLC2A5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A5→partner) and Y-score (partner→SLC2A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	5-Fluorouracil →	+0.604	+2.991	.027	.018	3	1
LARGE_INTESTINE	Eg5_9814 →	+0.585	+2.807	.034	.045	3	1
LARGE_INTESTINE	50869 →	+0.508	+2.871	.010	.021	3	1
LARGE_INTESTINE	630600 →	+0.661	+2.871	.024	.021	3	1
LARGE_INTESTINE	LMP744 →	+0.810	+2.871	.010	.021	3	1
LARGE_INTESTINE	I-BRD9 →	+0.518	+2.649	.007	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

5-Fluorouracil by SLC2A5 expression — LARGE_INTESTINE

Explore this box plot interactively →