SLC2A4RG

Across TCGA cell cohorts, SLC2A4RG mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A4RG-associated genes across cancer lineages are OPRPN, PLPPR1, and MS4A3. Each is linked with SLC2A4RG in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A4RG-to-partner and partner-to-SLC2A4RG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by SLC2A4RG-low versus SLC2A4RG-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A4RG→partner) and Y-score (partner→SLC2A4RG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPRPN →	+0.060	+5.087	<.001	.004	3	1
LARGE_INTESTINE	PLPPR1 →	+0.372	+3.285	.004	.008	3	1
LARGE_INTESTINE	MS4A3 →	+0.077	+3.285	.001	.007	3	1
LARGE_INTESTINE	MSGN1 →	+0.069	+3.345	<.001	.001	3	1
LARGE_INTESTINE	PNOC →	+0.040	+4.000	.002	.004	3	1
LARGE_INTESTINE	C12orf40 →	+0.006	+3.099	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

OPRPN by SLC2A4RG expression — URINARY_TRACT

Explore this box plot interactively →