SLC2A4

Across TCGA patient cohorts, SLC2A4 mutation is significantly associated with the RNA expression of many other genes, with 3,698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A4-associated genes across cancer lineages are PANK4, FANCC, and SAFB. Each is linked with SLC2A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC2A4-to-partner and partner-to-SLC2A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PANK4 grouped by SLC2A4-low versus SLC2A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A4→partner) and Y-score (partner→SLC2A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PANK4 →	+0.310	+1.868	.001	<.001	3	3
UCEC	FANCC →	+0.403	+1.958	<.001	.002	3	3
UCEC	SAFB →	+0.252	+2.436	.003	.001	3	3
SKCM	LMNB2 →	+0.837	+3.331	<.001	.005	3	3
CESC	ACTG1P13 →	+0.051	+5.812	<.001	.003	3	3
UCEC	UPF1 →	+0.288	+1.669	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,698 associations by consensus.

PANK4 by SLC2A4 expression — UCEC

Explore this box plot interactively →