SLC2A4

Across TCGA cell cohorts, SLC2A4 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A4-associated genes across cancer lineages are MAGEB5, HBZ, and TBR1. Each is linked with SLC2A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A4-to-partner and partner-to-SLC2A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by SLC2A4-low versus SLC2A4-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A4→partner) and Y-score (partner→SLC2A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LARGE_INTESTINE	HBZ →	+0.039	+2.994	.009	.006	3	1
LARGE_INTESTINE	TBR1 →	+0.042	+3.584	<.001	.003	3	1
LARGE_INTESTINE	TTLL8 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	COX6A2 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

MAGEB5 by SLC2A4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →