SLC2A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC2A3 mutation is significantly associated with the RNA expression of many other genes, with 3,237 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A3-associated genes across cancer lineages are RNU6-24P, LINC01496, and GAPDHP24. Each is linked with SLC2A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC2A3-to-partner and partner-to-SLC2A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-24P grouped by SLC2A3-low versus SLC2A3-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A3→partner) and Y-score (partner→SLC2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRNU6-24P →+0.392+5.039<.001.00834
SKCMLINC01496 →+0.053+3.186<.001.00634
BRCAGAPDHP24 →+0.089+4.401<.001.00233
UCECMIR6803 →+0.122+4.205<.001<.00133
HNSCTOR1BP1 →+0.278+3.801<.001.00933
READMIR367 →+0.570+5.039<.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,237 associations by consensus.

RNU6-24P by SLC2A3 expression — READ

Box plot of RNU6-24P in SLC2A3-low vs SLC2A3-high samples in READ.

Explore this box plot interactively →

Exploration