SLC2A3

Across TCGA cell cohorts, SLC2A3 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC2A3-associated genes across cancer lineages are GHRHR, C20orf85, and IL22. Each is linked with SLC2A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A3-to-partner and partner-to-SLC2A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by SLC2A3-low versus SLC2A3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A3→partner) and Y-score (partner→SLC2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GHRHR →	+0.387	+3.705	<.001	.007	3	1
BLOOD_Leukemia	C20orf85 →	+0.029	+4.384	<.001	.006	3	1
BLOOD_Leukemia	IL22 →	+0.030	+4.984	<.001	.002	3	1
BLOOD_Leukemia	TLX3 →	+1.621	+3.944	<.001	.006	3	1
BLOOD_Leukemia	FAM71B →	+0.023	+4.060	<.001	.003	3	1
BLOOD_Leukemia	OR10K2 →	+0.051	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

GHRHR by SLC2A3 expression — BLOOD_Leukemia

Explore this box plot interactively →