SLC2A14

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC2A14 mutation is significantly associated with the RNA expression of many other genes, with 4,183 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A14-associated genes across cancer lineages are FAM86DP, C16orf95, and CCM2L. Each is linked with SLC2A14 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC2A14-to-partner and partner-to-SLC2A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM86DP grouped by SLC2A14-low versus SLC2A14-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A14→partner) and Y-score (partner→SLC2A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMFAM86DP →+0.485+2.247.004.00534
UCECC16orf95 →+0.288+2.369<.001<.00133
UCECCCM2L →-0.365-3.774.004<.00133
SKCMADAM33 →-0.409-1.861.004<.00133
UCECSFR1 →+0.370+2.086.003<.00133
SKCMTMEM176A →-0.810-1.575.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,183 associations by consensus.

FAM86DP by SLC2A14 expression — SKCM

Box plot of FAM86DP in SLC2A14-low vs SLC2A14-high samples in SKCM.

Explore this box plot interactively →

Exploration