SLC2A14

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC2A14 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A14-associated genes across cancer lineages are CHIA, TRPC6, and LHCGR. Each is linked with SLC2A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A14-to-partner and partner-to-SLC2A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHIA grouped by SLC2A14-low versus SLC2A14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A14→partner) and Y-score (partner→SLC2A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECHIA →+0.040+3.760<.001<.00131
LARGE_INTESTINETRPC6 →+0.524+3.966.001.00431
LARGE_INTESTINELHCGR →+0.034+3.297<.001.00231
LARGE_INTESTINEUCMA →+0.015+3.217<.001.00631
LUNG_NSCLC_LUADOR1N1 →+0.035+3.734<.001.00631
LUNG_NSCLC_LUADOR4X2 →+0.018+3.947<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CHIA by SLC2A14 expression — LARGE_INTESTINE

Box plot of CHIA in SLC2A14-low vs SLC2A14-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration