SLC2A12

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC2A12 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC2A12-associated genes across cancer lineages are IL36A, PAX1, and CHST9. Each is linked with SLC2A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A12-to-partner and partner-to-SLC2A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL36A grouped by SLC2A12-low versus SLC2A12-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A12→partner) and Y-score (partner→SLC2A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaIL36A →+0.914+3.656<.001.00632
BLOOD_LeukemiaPAX1 →+0.030+3.890<.001<.00131
BLOOD_LeukemiaCHST9 →+0.018+3.814.001.00231
BLOOD_LeukemiaTRAT1 →+3.322+3.491<.001.00931
BLOOD_LeukemiaCALHM4 →+0.020+3.269<.001.00731
BLOOD_LeukemiaKRT6C →+0.016+3.359<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

IL36A by SLC2A12 expression — BLOOD_Leukemia

Box plot of IL36A in SLC2A12-low vs SLC2A12-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration