SLC2A11

Across TCGA patient cohorts, SLC2A11 mutation is significantly associated with the RNA expression of many other genes, with 2,166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A11-associated genes across cancer lineages are C18orf25, MPPE1, and FAM210A. Each is linked with SLC2A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC2A11-to-partner and partner-to-SLC2A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf25 grouped by SLC2A11-low versus SLC2A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A11→partner) and Y-score (partner→SLC2A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C18orf25 →	+0.519	+3.716	<.001	<.001	3	3
UCEC	MPPE1 →	+0.399	+2.708	.006	.003	3	3
UCEC	FAM210A →	+0.526	+3.364	<.001	.004	3	3
UCEC	SZRD1 →	+0.312	+3.721	.004	<.001	3	3
UCEC	TIMM21 →	+0.539	+2.823	<.001	.001	3	3
UCEC	WDR7 →	+0.332	+3.625	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,166 associations by consensus.

C18orf25 by SLC2A11 expression — UCEC

Explore this box plot interactively →