SLC2A11

Across TCGA patient cohorts, SLC2A11 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A11-associated genes across cancer lineages are eIF4E, GAPDH, and JNK2. Each is linked with SLC2A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A11-to-partner and partner-to-SLC2A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC2A11-low versus SLC2A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A11→partner) and Y-score (partner→SLC2A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.219	+3.183	.017	.009	3	2
COAD	GAPDH →	+0.568	+2.467	.009	.011	3	2
UCEC	JNK2 →	+0.348	+3.906	<.001	<.001	3	2
UCEC	MEK1 →	+0.442	+3.459	.005	.005	3	2
COAD	E-Cadherin →	-0.542	-2.450	.048	.020	3	2
SKCM	ACC_pS79 →	+0.433	+3.169	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

eIF4E by SLC2A11 expression — UCEC

Explore this box plot interactively →