SLC2A11

Across TCGA cell cohorts, SLC2A11 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC2A11-associated genes across cancer lineages are KRTAP10-5, SIGLEC6, and WNT8A. Each is linked with SLC2A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A11-to-partner and partner-to-SLC2A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-5 grouped by SLC2A11-low versus SLC2A11-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A11→partner) and Y-score (partner→SLC2A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.011	+4.078	<.001	.009	3	1
SKIN	SIGLEC6 →	+0.171	+3.544	<.001	.007	3	1
SKIN	WNT8A →	+0.013	+3.345	<.001	.007	3	1
LARGE_INTESTINE	MRO →	+0.241	+3.392	.004	.006	3	1
LARGE_INTESTINE	VAX1 →	+0.646	+3.782	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

KRTAP10-5 by SLC2A11 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →