SLC29A4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC29A4 mutation is significantly associated with the RNA expression of many other genes, with 981 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A4-associated genes across cancer lineages are RNA5SP426, OR4F15, and DUXAP3. Each is linked with SLC29A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC29A4-to-partner and partner-to-SLC29A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP426 grouped by SLC29A4-low versus SLC29A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A4→partner) and Y-score (partner→SLC29A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP426 →+0.153+3.038<.001.00633
HNSCOR4F15 →+0.063+5.303<.001.00632
CESCDUXAP3 →+0.132+4.236<.001.00132
CESCRNU6-1019P →+0.510+4.391<.001.00132
CESCRNU6-1245P →+0.279+3.475<.001.00832
UCECLINC02340 →+0.391+1.981<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 981 associations by consensus.

RNA5SP426 by SLC29A4 expression — UCEC

Box plot of RNA5SP426 in SLC29A4-low vs SLC29A4-high samples in UCEC.

Explore this box plot interactively →

Exploration