SLC29A4

Across TCGA patient cohorts, SLC29A4 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A4-associated genes across cancer lineages are Cyclin-B1, 14-3-3_beta, and EGFR. Each is linked with SLC29A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A4-to-partner and partner-to-SLC29A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by SLC29A4-low versus SLC29A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A4→partner) and Y-score (partner→SLC29A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.627	+2.222	.008	.011	3	2
UCEC	14-3-3_beta →	-0.113	-2.295	.007	.033	3	1
UCEC	EGFR →	-0.137	-3.000	.044	.036	3	1
UCEC	ERK2 →	+0.234	+3.459	.004	.005	3	1
UCEC	FOXO3a →	+0.114	+1.713	.007	.027	3	1
UCEC	MEK1 →	+0.454	+3.321	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Cyclin-B1 by SLC29A4 expression — UCEC

Explore this box plot interactively →