SLC29A2

Across TCGA patient cohorts, SLC29A2 mutation is significantly associated with the RNA expression of many other genes, with 740 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A2-associated genes across cancer lineages are MTCYBP32, IGHV3-33, and RNU6-781P. Each is linked with SLC29A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A2-to-partner and partner-to-SLC29A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCYBP32 grouped by SLC29A2-low versus SLC29A2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A2→partner) and Y-score (partner→SLC29A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MTCYBP32 →	+0.031	+5.305	<.001	.003	3	2
UCEC	IGHV3-33 →	+2.109	+2.711	.001	.003	3	2
UCEC	RNU6-781P →	+0.362	+2.463	<.001	.002	3	2
UCEC	RN7SL592P →	+0.178	+2.345	.001	.002	3	2
SKCM	PRPF4BP1 →	+0.219	+2.914	<.001	.006	3	2
UCEC	TBC1D2B →	+0.530	+2.721	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 740 associations by consensus.

MTCYBP32 by SLC29A2 expression — LIHC

Explore this box plot interactively →