SLC29A2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC29A2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A2-associated genes across cancer lineages are Caspase-7-cleavedD198, PKC-a_pS657, and PKC-a. Each is linked with SLC29A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A2-to-partner and partner-to-SLC29A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC29A2-low versus SLC29A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A2→partner) and Y-score (partner→SLC29A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.755+3.019.015.01932
UCECPKC-a_pS657 →+0.598+3.335.002.00531
UCECPKC-a →+0.625+2.820.003.03531
UCECPKC-delta_pS664 →+0.154+2.817.014.03631
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Caspase-7-cleavedD198 by SLC29A2 expression — UCEC

Box plot of Caspase-7-cleavedD198 in SLC29A2-low vs SLC29A2-high samples in UCEC.

Explore this box plot interactively →

Exploration