SLC29A2

Across TCGA cell cohorts, SLC29A2 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC29A2-associated genes across cancer lineages are PHOX2B, MYOD1, and TBC1D21. Each is linked with SLC29A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A2-to-partner and partner-to-SLC29A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHOX2B grouped by SLC29A2-low versus SLC29A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A2→partner) and Y-score (partner→SLC29A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PHOX2B →	+0.032	+4.362	<.001	.005	3	2
LARGE_INTESTINE	MYOD1 →	+0.014	+3.684	<.001	.006	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
BLOOD_Leukemia	NKAIN4 →	+1.377	+2.660	.004	.008	3	1
OVARY	IFNA17 →	+0.020	+5.807	<.001	.001	3	1
BLOOD_Leukemia	EXOSC9 →	+0.673	+3.176	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

PHOX2B by SLC29A2 expression — LARGE_INTESTINE

Explore this box plot interactively →