SLC29A1

Across TCGA pan-cancer cohorts, SLC29A1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated SLC29A1 data layer compared with 24 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher SLC29A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC29A1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

THYM, KIRC, and SCLC are the cancer types where SLC29A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
KIRC	OS	Median	All	0.134	0.811	<.001	30	view →
SCLC	OS	Median	II,III,IV	0.192	0.699	.002	18	view →
BLCA	OS	Median	III,IV	0.381	0.691	.013	8	view →
SARC	OS	Median	All	0.144	0.745	.001	6	view →
UCEC	DFS	Median	All	0.959	0.632	.027	4	view →
ESCA	DFS	Median	II,III,IV	0.216	0.524	.045	3	view →
COAD	DFS	Median	II,III,IV	0.200	0.648	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

SLC29A1–THYM (OS)

Open the THYM breakdown →