SLC28A3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC28A3 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC28A3-associated genes across cancer lineages are p62 Lck ligand, Shc_pY317, and CDK1. Each is linked with SLC28A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC28A3-to-partner and partner-to-SLC28A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC28A3→partner) and Y-score (partner→SLC28A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp62 Lck ligand →+0.280+2.222.043.01132
UCECShc_pY317 →-0.213-2.700<.001.00632
UCECCDK1 →+0.132+2.321.040.03432
UCECCyclin-B1 →+0.632+2.906.007.00132
UCECEGFR_pY1068 →-0.273-2.906.010.00131
UCECERK2 →+0.197+2.999.015.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration