SLC28A2

Across TCGA patient cohorts, SLC28A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,017 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SLC28A2-associated GO terms across cancer lineages are Regulation of double-strand break repair, Positive regulation of double-strand break repair, and Positive regulation of DNA repair. Each is linked with SLC28A2 in more than 20 cancer types. Because this analysis shows association rather than direction, both SLC28A2-to-partner and partner-to-SLC28A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by SLC28A2-low versus SLC28A2-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC28A2→partner) and Y-score (partner→SLC28A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of double-strand break repair →	+0.056	+0.222	<.001	<.001	3	21
SCLC	Positive regulation of double-strand break repair →	+0.086	+0.241	<.001	<.001	3	21
SCLC	Positive regulation of DNA repair →	+0.063	+0.232	<.001	<.001	3	21
SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.096	+0.234	<.001	<.001	3	20
ESCA	Glycerolipid biosynthetic process →	+0.037	+0.829	.001	.004	3	20
SCLC	Telomere maintenance →	+0.092	+0.368	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,017 associations by consensus.

Regulation of double-strand break repair by SLC28A2 expression — SCLC

Explore this box plot interactively →