SLC28A2

Across TCGA cell cohorts, SLC28A2 mutation is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC28A2-associated genes across cancer lineages are SPATA22, C1QB, and AZIN2. Each is linked with SLC28A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC28A2-to-partner and partner-to-SLC28A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA22 grouped by SLC28A2-low versus SLC28A2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC28A2→partner) and Y-score (partner→SLC28A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPATA22 →	+0.638	+3.551	<.001	.009	3	1
BLOOD_Leukemia	C1QB →	+0.166	+4.691	<.001	<.001	3	1
LARGE_INTESTINE	AZIN2 →	+0.932	+3.212	.002	.006	3	1
LARGE_INTESTINE	IRAK1BP1 →	+0.665	+3.212	.001	.006	3	1
LARGE_INTESTINE	TYW3 →	+0.673	+3.082	.006	.007	3	1
LARGE_INTESTINE	GNL3 →	+0.567	+3.212	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

SPATA22 by SLC28A2 expression — BLOOD_Leukemia

Explore this box plot interactively →