SLC28A1

Across TCGA cell cohorts, SLC28A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,041 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC28A1-associated GO terms across cancer lineages are Negative regulation of innate immune response, Cellular response to type I interferon, and Cell communication involved in cardiac conduction. Each is linked with SLC28A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC28A1-to-partner and partner-to-SLC28A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of innate immune response grouped by SLC28A1-low versus SLC28A1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC28A1→partner) and Y-score (partner→SLC28A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of innate immune response →	+0.112	+0.685	.001	.002	3	6
BLOOD_Lymphoma	Cellular response to type I interferon →	+0.098	+0.024	.001	.006	3	5
BREAST	Cell communication involved in cardiac conduction →	+0.146	+0.462	.001	.002	3	5
BREAST	Bundle of His cell to Purkinje myocyte communication →	+0.310	+0.515	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	CD8-positive, alpha-beta T cell homeostasis →	+0.115	+0.058	<.001	.004	2	6
BREAST	Negative regulation of tumor necrosis factor production →	+0.126	+0.686	<.001	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

Negative regulation of innate immune response by SLC28A1 expression — BREAST

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