SLC28A1

Across TCGA cell cohorts, SLC28A1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC28A1-associated genes across cancer lineages are SMCP, CEACAM4, and OR4X2. Each is linked with SLC28A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC28A1-to-partner and partner-to-SLC28A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMCP grouped by SLC28A1-low versus SLC28A1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC28A1→partner) and Y-score (partner→SLC28A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SMCP →	+0.197	+5.321	<.001	.005	3	2
CNS	CEACAM4 →	+0.068	+5.321	<.001	.005	3	1
CNS	OR4X2 →	+0.027	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	OCM2 →	+0.051	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR10C1 →	+0.050	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRAMEF11 →	+0.004	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

SMCP by SLC28A1 expression — CNS

Explore this box plot interactively →