SLC27A6

Across TCGA patient cohorts, SLC27A6 mutation is significantly associated with the RNA expression of many other genes, with 6,055 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A6-associated genes across cancer lineages are GLRX5, ZMYND19, and ZPR1. Each is linked with SLC27A6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC27A6-to-partner and partner-to-SLC27A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLRX5 grouped by SLC27A6-low versus SLC27A6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A6→partner) and Y-score (partner→SLC27A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GLRX5 →	+0.439	+2.842	.001	.001	3	4
UCEC	ZMYND19 →	+0.668	+3.576	<.001	<.001	3	4
UCEC	ZPR1 →	+0.460	+2.743	<.001	<.001	3	4
LUSC	SLIRP →	+0.475	+3.459	.001	.005	2	5
UCEC	RPF2P1 →	+0.177	+1.799	<.001	.001	3	3
UCEC	TAF9 →	+0.692	+3.544	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,055 associations by consensus.

GLRX5 by SLC27A6 expression — LUSC

Explore this box plot interactively →