SLC27A6

Across TCGA patient cohorts, SLC27A6 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A6-associated genes across cancer lineages are GAPDH, FASN, and C-Raf. Each is linked with SLC27A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC27A6-to-partner and partner-to-SLC27A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC27A6-low versus SLC27A6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A6→partner) and Y-score (partner→SLC27A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.347	+1.700	.040	.040	3	4
UCEC	FASN →	+0.361	+1.678	.003	.021	3	3
UCEC	C-Raf →	+0.171	+1.925	<.001	.004	3	3
UCEC	FoxM1 →	+0.270	+2.115	<.001	<.001	3	2
UCEC	PDCD4 →	-0.621	-1.584	<.001	.005	3	2
UCEC	RAD51 →	+0.089	+1.584	.042	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

GAPDH by SLC27A6 expression — UCEC

Explore this box plot interactively →